Plasma toxic shock syndrome toxin-1(TSST-1) levels and hemodynamic change in the rabbits after injection of TSST-1 and TSST-1 producible MRSA.

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Identification of Toxic Shock Syndrome Toxin-1 (TSST-1) gene in Staphylococcus aureus isolated from bovine mastitis milk

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[Evaluation of anti-toxic shock syndrome toxin-1 (TSST-1) antibody in severely burned patients].

序 文 広範囲熱傷患者は,皮 膚常在菌である黄色ブ ド ウ球菌が繁殖 しやす く,近 年のメチシ リン耐性株 の流行に伴い,創 感染ひいては敗血症に陥 り治療 に難渋する.特 に当施設においては,黄 色ブ ドウ 球菌の94%が メチシ リン耐性で さらにその うち 96%がTSST-1産 生株であ り1),それが感染症の重 篤化になんらかの影響を及ぼしていることが想定 される.そ こで研究の第一段階として,広 範囲熱 傷患者血清中のTSST-1に 対す る抗体 である抗 TSST-1抗 体価を測定 し,臨 床的意義について検 討した. 材料 と方法 対象は気道内,創 部等よりマンニット分解,食 塩耐性,コ アグラーゼ陽性の基準にて同定 した Staphylococcusaureusが 分離検出 された広範囲 熱傷患者16例 である(平 均年齢44.8±17.4歳,平 均熱傷面積48....

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Environmental factors affecting toxic shock syndrome toxin-1 (TSST-1) synthesis.

The production of toxic shock syndrome toxin-1 (TSST-1) was studied in batch and continuous culture of Staphylococcus aureus strain 1169 in a carbohydrate-free chemically defined medium (CDM). In continuous culture oxygen- and arginine-limitation were required for steady-state TSST-1 synthesis. Aeration suppressed toxin synthesis. The amount of TSST-1 per mg dry weight (specific toxin) at dilut...

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Toxic shock syndrome toxin 1 (TSST-1) production by staphylococci isolated from goats and presence of specific antibodies to TSST-1 in serum and milk.

The ability of staphylococcal strains isolated from different anatomical sites in 133 healthy goats to produce toxic shock syndrome toxin 1 (TSST-1) and the presence of antibodies to this toxin in serum and milk were studied. The enzyme-linked immunosorbent assay method was used to detect both the toxin and the presence of antibodies. Of a total of 342 staphylococcal strains studied, 86 (25.2%)...

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identification of toxic shock syndrome toxin-1 (tsst-1) gene in staphylococcus aureus isolated from bovine mastitis milk

staphylococcus aureus is a major causative pathogen of clinical and subclinical mastitis of dairy domestic ruminants. this agent produces a variety of extracellular toxins and virulence factors including toxic shock syndrome toxin-1 (tsst-1) which is the major cause of toxic shock syndrome (tss). in this study 58 s. aureus isolates obtained from 9 dairy herds in east and west azerbaijan prov...

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ژورنال

عنوان ژورنال: Nihon Kyukyu Igakukai Zasshi

سال: 1997

ISSN: 1883-3772,0915-924X

DOI: 10.3893/jjaam.8.65